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Heidelberg, 6 February 2020 Scientists explore how females shut off their second X chromosome In their landmark research published in Nature on 5 February, the scientists reveal how SPEN targets and silences active genes on the X chromosome, providing important new insights into the molecular basis of X-inactivation.
Heidelberg, 20 January 2020 Melting reveals drug targets in a living organism An international team led by researchers at EMBL Heidelberg and Cellzome, a GSK company, has developed a technology to systematically identify drug targets in living animals. In their results, published in Nature Biotechnology on 20 January, the scientists mapped protein–drug interactions in rat organs and blood. Their research opens pathways in drug discovery, fundamental biology, and personalised medicine.
Heidelberg, 23 December 2019 EMBL co-develops new method that could facilitate cancer diagnosis Researchers led by EMBL Heidelberg and the Center for Bioinformatics at Saarland University have developed a cheaper and faster method to check for genetic differences in individual cells, which outperforms existing techniques with respect to the information received. This new method could become a new standard in single cell research, and potentially for clinical diagnosis in disease genetics, including cancer. The results have been published in Nature Biotechnology.
Heidelberg, 23 December 2019 Innovative method delivers new insights into the stem cell microenvironment Researchers from EMBL and the German Cancer Research Center (DKFZ) in Heidelberg, Germany, have developed new methods to reveal the three-dimensional organisation of bone marrow at a single cell level. Since bone marrow harbours blood stem cells responsible for life-long blood generation, these results and the new method provides a novel scientific basis to study blood cancer. The results have been published in Nature Cell Biology.
Hinxton, 13 December 2019 Machine learning finds functional human phosphosites Researchers at the EMBL’s European Bioinformatics Institute (EMBL-EBI) have created the largest reference phosphoproteome to date of almost 120 000 human phosphosites. To identify those most likely to be critical, they used a machine learning approach capable of ranking them according to functional importance.
Heidelberg, 2 December 2019 EMBL and Leica sign open innovation collaboration agreement EMBL often cooperates with industry partners, and has cooperated successfully with Leica for many years. Based on this strong partnership, Leica is among the companies supporting the upcoming EMBL Imaging Centre, which is currently under construction at the EMBL campus in Heidelberg, Germany.
Heidelberg, 7 November 2019 Integrating imaging research across Europe The European Commission has officially established Euro-BioImaging – which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging – as a European Research Infrastructure Consortium (ERIC). Since Euro-BioImaging was initiated at EMBL in 2007, this adds yet another remarkable achievement to EMBL’s mission of integrating European life sciences.
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