Neutron protein crystallography provides a powerful complement to X-ray diffraction by enabling key details of the hydrogen atom and water structure in protein crystal structures to be revealed. Applications include direct visualization of hydrogen atoms at catalytic sites in enzymes and the location of lipids, detergents and other disordered groups in crystals that often cannot be seen by X-ray analysis alone.
Neutron protein crystallography beamlines
EMBL Grenoble collaborates with the ILL to provide access to the follwoing neutron crystallography beamline:
- LADI (Laue diffractometer dedicated to neutron protein crystallography at high-resolution)